Nature’s Essentials’ Bioavailable Biotin active ingredients are always found in nature and derived from natural sources, with our advanced Cyclostome™ Technology for maximum absorption and solubility. Our Cyclostome™ Technology increases absorption by protecting the Biotin from stomach acids with natural phospholipids; after all, the normal range for Biotin bioavailability falls in the range of 20-40%.
Biotin is an essential nutrient (coenzyme B vitamin) for normal cell growth and body function, promotes immune health, and plays a critical role in supporting healthy radiant hair, vibrant skin, and strong nails. Biotin also supports the metabolism of fats, carbohydrates, and proteins for optimum energy use in the body. Biotin is essential for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. Biotin assists in various metabolic reactions involving the transfer of carbon dioxide. Biotin may also be helpful in maintaining a healthy blood sugar levels.
Nature’s Essentials’ Biotin combines the highest quality Biotin active ingredients, which are always found in nature and derived from natural sources, with our advanced Cyclosome™ Technology for maximum absorption and potency. Our Cyclostome™ Technology increases absorption by protecting the Biotin from stomach acids with natural phospholipids; after all, the normal range for Biotin bioavailability falls in the range of 20-40%. Biotin is an essential nutrient (coenzyme B vitamin) for normal cell growth and body function, promotes immune health, and plays a critical role in supporting healthy radiant hair, vibrant skin, and strong nails. Biotin also supports the metabolism of fats, carbohydrates, and proteins for optimum energy use in the body. Biotin is essential for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. Biotin assists in various metabolic reactions involving the transfer of carbon dioxide. Biotin may also be helpful in maintaining a healthy blood sugar levels.
A number of metabolic disorders exist in which an individual’s metabolism of Biotin is abnormal, such as deficiency in the holocarboxylase synthetase enzyme which covalently links biotin onto the carboxylase, where the biotin acts as a cofactor.
High doses of biotin may play a role in stopping and reversing progression in progressive multiple sclerosis, as shown in a small pilot study of 23 patients in France. 91% of these patients were judged to have improved clinically. [“High doses of biotin in chronic progressive multiple sclerosis: A pilot study”. Multiple Sclerosis and Related Disorders 4: 159–169. doi:10.1016/j.msard.2015.01.005. ] There was a 2 to 8 month lag in improvements. There are few treatment options for progressive MS.
Biotin is a heterocyclic, S-containing monocarboxylic acid. It is made from two precursors, alanine and pimeloyl-CoA via three enzymes. 8-Amino-7-oxopelargonic acid synthase is a pyridoxal 5′-phosphate enzyme. The pimeloyl-CoA, could be produced by a modified fatty acid pathway involving a malonyl thioester as the starter. 7,8Diaminopelargonic acid (DAPA) aminotransferase is unusual in using S-adenosyl methionine (SAM) as the NH2 donor. Dethiobiotin synthethase catalyzes the formation of the ureido ring via a DAPA carbamate activated with ATP. Biotin synthase reductively cleaves SAM into a deoxyadenosyl radical—a first radical formed on dethiobiotin is trapped by the sulfur donor, which was found to be the iron-sulfur (Fe-S) center contained in the enzyme. [Marquet A, Bui BT, Florentin D (2001). “Biosynthesis of biotin and lipoic acid”. Vitam. Horm. Vitamins & Hormones 61: 51–101.]
†These statements have not been evaluated by the FDA. This Product is not intended to diagnose, treat, cure or prevent any disease.
